CLINICAL APPLICATION OF EXOSOMES IN COSMETICS, SKIN CARE, TISSUE REGENERATION AND DERMATOLOGICAL DISEASES
Abstract
Exosomes are a subset of extracellular vesicles. Exosomes range from 40 to 160 nm in diameter and contain various genetic materials, including DNA, RNA, mRNA, metabolites, proteins, and lipids. Recent breakthroughs have revealed several therapeutic applications, including cosmetics, skincare, tissue regeneration, and dermatological illnesses. This research investigates the clinical uses of exosomes in dermatology and cosmetics, appraises their therapeutic potential for treating dermatological problems, and determines how well they work in skincare and tissue regeneration. A substantial body of research has been conducted on the clinical application of exosomes in dermatology, as indicated by the 60% of the studies that highlight their therapeutic potential in dermatological disorders; roughly 25% of the research focuses on skincare and cosmetic applications, indicating the increasing interest in using exosomes to improve skin health and appearance; the remaining 15% of studies investigate the role of exosomes in tissue regeneration, emphasizing their potential to speed up wound healing and tissue repair; the use of cutting edge software tools, such as Covidence and Rayyan, in the data analysis process has guaranteed a high degree of accuracy and reliability in these results, indicating a robust and developing field of study.
Downloads
References
Kalluri, R., & Lebleu, V. S. (2020). The Biology, Function, And Biomedical
Applications Of Exosomes. Science, 367(6478), Eaau6977.
Doi:10.1126/Science.Aau6977.
Liu, Y., Li, L., & Zhang, X. (2020). Exosomes: The New Frontier Of
Cosmetics. Journal Of Cosmetic Dermatology, 19(8), 1994-2001.
Doi:10.1111/Jocd.13287.
Zhu, W., & Xu, Y. (2019). Exosome-Based Novel Strategies For Tissue
Regeneration. Journal Of Tissue Engineering And Regenerative Medicine,
(7), 1194-1203. Doi:10.1002/Term.2911.
Gulati, K., & Shah, N. (2023). The Role Of Exosomes In Dermatological
Disorders: A Review. Journal Of Dermatological Science, 112(1), 3-14.
Doi:10.1016/J.Jdermsci.2022.11.004.
Jiang, Y., & Li, J. (2021). Exosome-Based Delivery Systems In Dermatology.
Dermatology And Therapy, 11(1), 85-96. Doi:10.1111/Dth.14988.
Liu, Y., Chen, C., & Chen, L. (2024). Advancements In Exosome-Based
Therapeutics For Cosmetic And Dermatological Applications. Journal Of
Controlled Release, 356, 312-326. Doi:10.1016/J.Jconrel.2024.02.014.
Yao, X., Xu, Y., & Zhang, J. (2023). Exosome-Based Approaches For Tissue
Regeneration And Dermatological Disease Treatment. Frontiers In
Bioengineering And Biotechnology, 11, 1002134.
Doi:10.3389/Fbioe.2023.1002134.
Wang, X., Li, Q., & Chen, J. (2022). The Role Of Exosomes In Dermatology:
From Basic Research To Clinical Application. Journal Of Dermatological
Science, 108(2), 109-118. Doi:10.1016/J.Jdermsci.2022.07.002.
Zhang, W., & Wang, S. (2021). Exosomes In Cosmetics And Skin Care:
Current Advances And Future Perspectives. Journal Of Cosmetic
Dermatology, 20(6), 1686-1697. Doi:10.1111/Jocd.13765.
Gao, L., & Liu, Y. Oh Et Al Wong Et Al. (2020). Exosomes In Skin
Regeneration And Wound Healing: A Review Of Mechanisms And
Applications. Advanced Drug Delivery Reviews, 155, 41-54.
Doi:10.1016/J.Addr.2020.01.003.
Jiang, X., & Chen, W. (2019). Therapeutic Potential Of Exosomes In
Dermatological Disorders: A Review. Dermatology And Therapy, 32(3), 401-
Doi:10.1111/Dth.12835.
Zhao, Y., & Zhang, X. (2018). Exosome-Based Drug Delivery Systems In
Dermatology: Recent Developments And Challenges. Journal Of Drug
Targeting, 26(5), 439-450. Doi:10.1080/1061186x.2018.1480771.
Yang, J., & Sun, Y. (2019). Exosome-Based Therapeutics In Cosmetic
Dermatology: Mechanisms And Applications. Cosmetic Dermatology, 27(3),
-238. Doi:10.1016/J.Cosder.2019.04.003.
Higgins, J. P. T., & Green, S. (2021). Cochrane Handbook For Systematic
Reviews Of Interventions. John Wiley & Sons.
Gao, J., & Xu, L. (2020). Best Practices For Data Management In Clinical
Trials Of Exosome-Based Treatments. Journal Of Clinical Trials, 11(2), 123-
Doi:10.4172/2167-0870.1000123.
Miller, P., & Berner, J. (2020). Inclusion And Exclusion Criteria In Clinical
Research: A Review. Journal Of Clinical Research, 21(5), 102-110.
Doi:10.1177/1740774520910769.
Zhu, M., & Li, X. (2023). Statistical Approaches In Evaluating ExosomeBased Therapies For Skin Care And Regenerative Medicine: A
Comprehensive Review. Statistical Medicine Journal, 42(8), 1152-1170.
Doi:10.1002/Sim.9447.
Kim, H. J., Lee, S. Y., & Choi, M. H. (2023). "Exosome-Based Strategies For
Skin Hydration And Barrier Function." Journal Of Cosmetic Dermatology,
(4), 123-135.
Zhang, L., Wang, Y., & Li, Z. (2024). "The Role Of Exosomes In The
Modulation Of Skin Elasticity And Collagen Production." Journal Of
Dermatological Science, 54(2), 88-102.
Zhang, Y., Liu, Y., Liu, H., & Wang, H. (2022). Exosomes In Tissue
Regeneration: An Emerging Therapeutic Strategy. Journal Of Cellular
Biochemistry, 123(6), 897-907. Link
Xu, L., & Li, Y. (2023). Exosome-Based Therapies For Tissue Regeneration:
Current Status And Future Perspectives. Regenerative Medicine, 18(2), 451-
Link
Li, J., Et Al. (2023). "Clinical Applications Of Exosome-Based Therapies In
Dermatology: A Systematic Review." Dermatology Research And Practice,
, 680-688.
Wang, Y., Et Al. (2022). "Mesenchymal Stem Cell-Derived Exosomes In
Dermatology: A Review." Journal Of Dermatological Science, 106(3), 142-
Huang, L., & Zhang, L. (2022). The Role Of Exosomes In Skin Care And
Cosmetics: Advances And Challenges. Journal Of Cosmetic Dermatology,
(5), 1650-1661. Doi:10.1111/Jocd.14832.
Gao, Q., & Zhang, X. (2021). Exosome-Based Innovations In Cosmetic
Dermatology: A Comprehensive Review. Cosmetic Dermatology, 29(2), 112-
Doi:10.1016/J.Cosder.2021.02.005.
Jiang, S., & Chen, X. (2023). Exosome-Based Therapies For Tissue
Regeneration: Current Progress And Future Directions. Regenerative
Medicine, 18(3), 549-562. Doi:10.2217/Rme-2022-0094.
Lee, H., & Lee, J. (2022). Exosome-Mediated Strategies For Wound Healing:
A Review Of Clinical Applications. Journal Of Tissue Engineering And
Regenerative Medicine, 16(4), 481-490. Doi:10.1002/Term.3284.
Zhang, M., & Liu, Y. (2021). Exosome-Based Approaches In Dermatological
Disease Management. Journal Of Dermatological Science, 103(2), 117-127.
Doi:10.1016/J.Jdermsci.2021.01.007.
Wang, Y., & Xu, Q. (2020). Therapeutic Potential Of Exosomes In Treating
Dermatological Disorders: Evidence And Perspectives. Dermatology And
Therapy, 33(5), E13356. Doi:10.1111/Dth.13356.
Li, X., & Zhang, W. (2023). Exosome-Based Therapeutics In Dermatology:
Recent Advances And Future Directions. Frontiers In Medicine, 10, 871407.
Doi:10.3389/Fmed.2023.871407.
Downloads
Published
Issue
Section
License
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation .
No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.
