To evaluate PCO2 –gap as earlier marker of tissue hypo perfusion and mortality predictor, compared to SCVO2 and lactate, in patients admitted with septic shock in medical ICU.
Keywords:
Tissue hypoperfusion, Mortiality predictorAbstract
The prime objective of present investigation was to assess arterial and venous PCO2 –gap, in comparison to SCVO2 and lactate as valuable, earlier and reliable marker of tissue hypoxia and therefore mortality in septic shock patients. It was a retrospective observational study on patients admitted with SIRS, severe sepsis or septic shock, in medical ICU of Agha Khan University hospital in year 2014-2015. All the patients aged 16 or above, admitted in year 2014 -2015 at medical ICU of Agha Khan University Hospital with septic shock defined as per surviving sepsis guidelines The patient’s data were organized under categories of age, sex, source of infectious etiology, mechanical ventilation need, renal replacement therapy, co morbidities, and total length of hospital stay, ICU stay, outcome, and 28 days mortality. SPSS version 19.0 (statistical package for social sciences) was used to conduct statistical analyses. An independent sample t-test was applied for comparison of quantitative variables, whereas a chi square test was performed to examine categorical variables across the categories of survival and PCO2 gap.
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