Effect of Zinc on Febrile Seizure in Children: A CrossSectional Study
Keywords:
Febrile Seizures, Simple Febrile Seizures, Complex Febrile Seizures, Children, Serum Zinc Level.Abstract
Background: Febrile seizures are the most frequent kind of seizure associated with childhood abnormalities. Usually, children between the ages of six months and five years’ experience these seizures. There are two types of febrile seizures, each with a different level of complexity or simplicity. Simple febrile seizures usually happen once per 24 hours and last for 10 to 15 minutes on average. Complex febrile seizures, on the other hand, occur over the course of a single 24-hour period and involve several episodes. Objective: To find out how trace minerals like zinc affect febrile seizures in children. Study design: A case-control study Place and Duration: This study was conducted in Al-Aleem Medical College, Ghulab Devi Teaching Hospital Lahore from October 2022 to October 2023. Methodology: To ensure age and gender homogeneity, 40 children with febrile seizures were matched with 40 control children. The children that were part of the study ranged in age from 6 months to 5 years. Every child exhibiting febrile seizures had a clinical diagnosis made after radiological CT imaging and EEG testing. Every patient provided a 2-cc blood sample for zinc analysis and electrolyte profiling, and each participant's age was recorded as well. Results: The average age of the controls was 3.56 years, while the average age of people with febrile seizures was 3.53 years. There was no significant difference in the age of both groups. In the total number of participants, the majority were boys in both groups. The zinc levels of the children with febrile seizures and the control group differed significantly. Zinc levels did not significantly differ between simple and complex febrile seizures. Conclusion: Zinc levels in the blood are lower in children experiencing febrile seizures than in children who are not experiencing seizures.
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