Synthesis and characterization of some new prodrug polymer based on poly vinyl alcohol and study some application: as a biological model
Keywords:
synthesis, characterization, paracetamol, polyvinyl alcohol, prodrug polymers.Abstract
This study was suggested for synthesis a new polymer for polyvinyl alcohol reaction with aspirin and paracetamol as drugs, and these drugs carry carboxylic and amide groups after it’s conversation into acid chloride, and all probable techniques were used for identification the product compounds by FT-IR and!H-NMR spectrums, controlled drug release, swelling, viscosity of polymers and solubility were measured. Finally, the thermal analysis and biological activity were studied too.
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