REGENERATIVE ENDODONTIC THERAPY: REPORT OF TWO CASES WITH DIVERSE CLINICAL APPROACHES AND RESULT
Abstract
Treating necrotic immature permanent teeth through endodontic procedures often poses clinical challenges. However, with careful case selection, regenerative treatments can yield positive results. Yet, there remains a lack of consensus regarding the ideal disinfection protocol or method to ensure consistent clinical outcomes. This article showcases two cases of regenerative treatment in necrotic immature teeth. Each case utilized mineral trioxide aggregate (MTA) and Biodentine™ as coronal barriers along with different irrigants, resulting in distinct clinical outcomes.
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- Khetarpal A, Chaudhary S, Talwar S, Ravi R, Verma M. Revascularization of immature
permanent tooth with periapical lesion using a new biomaterial - A case report. Int J Dent Sci
Res. 2013 Sep;1(1):20-2.
- Rafter M. Apexification: a review. Dent Traumatol. 2005 Feb;21(1):1-8.
- Torabinejad M, Chivian N. Clinical applications of mineral trioxide aggregate. J Endod.
Mar;25(3):197-205.
- Nosrat A, Homayounfar N, Oloomi K. Drawbacks and unfavorable outcomes of
regenerative endodontic treatments of necrotic
immature teeth: a literature review and report of a case. J Endod. 2012 Oct;38(10):1428-34.
- Ding RY, Cheung GS, Chen J, Yin XZ, Wang QQ, Zhang CF. Pulp revascularization of
immature teeth with apical periodontitis: a clinical study. J Endod. 2009 May;35(5):745-9.
- Huang GT. A paradigm shift in endodontic management of immature teeth: conservation
of stem cells for regeneration. J Dent. 2008 Jun;36(6):379-86.
- Chen MY, Chen KL, Chen CA, Tayebaty F, Rosenberg PA, Lin LM. Responses of
immature permanent teeth with infected necrotic pulp tissue and apical periodontitis/abscess
to revascularization procedures. Int Endod J. 2012 Mar;45(3):294-305.
- Banchs F, Trope M. Revascularization of immature permanent teeth with apical
periodontitis: new treatment protocol? J Endod. 2004 Apr;30(4):196-200.
- Reynolds K, Johnson JD, Cohenca N. Pulp revascularization of necrotic bilateral bicuspids
using a modified novel technique to eliminate potential coronal discolouration: a case report.
Int Endod J. 2009 Jan;42(1):84-92.
- Shin SY, Albert JS, Mortman RE. One step pulp revascularization treatment of an
immature permanent tooth with chronic apical abscess: a case report. Int Endod J. 2009
Dec;42(12):1118-26.
- Petrino JA, Boda KK, Shambarger S, Bowles WR, McClanahan SB. Challenges in
regenerative endodontics: a case series. J Endod. 2010 Mar;36(3):536-41.
- Chueh LH, Huang GT. Immature teeth with periradicular periodontitis or abscess
undergoing apexogenesis: a paradigm shift. J Endod. 2006 Dec;32(12):1205-13.
- Chueh LH, Ho YC, Kuo TC, Lai WH, Chen YH, Chiang CP. Regenerative endodontic
treatment for necrotic immature permanent teeth. J Endod. 2009 Feb;35(2): 160-4.
- Thibodeau B, Trope M. Pulp revascularization of a necrotic infected
immature permanent tooth: case report and review of the literature. Pediatr Dent. 2007 JanFeb;29(1):47-50.
- Hoshino E, Kurihara-Ando N, Sato I, Uematsu H, Sato M, Kota K, et al. In-vitro
antibacterial susceptibility of bacteria taken from infected root dentine to a mixture of
ciprofloxacin, metronidazole and minocycline. Int Endod J. 1996 Mar;29(2):125-30.
- Hargreaves KM, Cohen S, Berman LH. Cohen's pathways of the pulp expert consult:
th ed. Mosby, St. Louis; 2011: 614.
- Considerations for Regenerative Procedures. [Internet]. American Association of
Endodontics. 2013. [cited October 1, 2013]. Available at: http://www.aae.org
- Levitan ME, Himel VT. Dens evaginatus: literature review, pathophysiology, and
comprehensive treatment regimen. J Endod. 2006 Jan;32(1):1-9.
- da Silva LA, Nelson-Filho P, da Silva RA, Flores DS, Heilborn C, Johnson JD, et al.
Revascularization and periapical repair after endodontic treatment using apical negative
pressure irrigation versus conventional irrigation plus triantibiotic intracanal dressing in dogs'
teeth with apical periodontitis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010
May;109(5):779-87.
- Trevino EG, Patwardhan AN, Henry MA, Perry G, Dybdal-Hargreaves N, Hargreaves
KM, et al. Effect of irrigants on the survival of human stem cells of the apical papilla in a
platelet-rich plasma scaffold in human root tips. J Endod. 2011 Aug;37(8):1109-15.
- Yamauchi N, Yamauchi S, Nagaoka H, Duggan D, Zhong S, Lee SM, et al. Tissue
engineering strategies for immature teeth with apical periodontitis. J Endod. 2011 Mar;37(3):
-7.
- Ring KC, Murray PE, Namerow KN, Kuttler S, Garcia-Godoy F. The comparison of the
effect of endodontic irrigation on cell adherence to root canal dentin. J Endod. 2008
Dec;34(12):1474-9.
- Zanini M, Sautier JM, Berdal A, Simon S. Biodentine induces immortalized murine pulp
cell differentiation into odontoblast-like cells and stimulates biomineralization. J Endod. 2012
Sep;38(9):1220-6.
- Lin LM, Shimizu E, Gibbs JL, Loghin S, Ricucci D. Histologic and histobacteriologic
observations of failed revascularization/ revitalization therapy: a case report. J Endod. 2014
Feb;40(2):291-5.
- Lenzi R, Trope M. Revitalization procedures in two traumatized incisors with different
biological outcomes. J Endod. 2012 Mar;38(3):411-4.
- Wang X, Thibodeau B, Trope M, Lin LM, Huang GT. Histologic characterization of
regenerated tissues in canal space after the revitalization/revascularization procedure of
immature dog teeth with apical periodontitis. J Endod. 2010 Jan;36(1):56-63.
- Fouad AF, Nosrat A. Pulp regeneration in previously infected root canal space. Endod
Topics. 2013 May;28(1):24-37.
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