Virchow’s node: historical and didactic features f the description of the eponym

Authors

  • Nikolay N. Krylov FSAEI HE I.M. Sechenov First MSMU MOH Russia (Sechenov University) 8 Trubetskaya St., building 2, Moscow 119991, Russia Author
  • Aftandil V. Alekberzade FSAEI HE I.M. Sechenov First MSMU MOH Russia (Sechenov University) 8 Trubetskaya St., building 2, Moscow 119991, Russia Author
  • Elena A. Piatenko FSAEI HE I.M. Sechenov First MSMU MOH Russia (Sechenov University) 8 Trubetskaya St., building 2, Moscow 119991, Russia Author

Keywords:

Virchow’s node, Troisier’s sign, the history of oncology, teaching in medical higher education institutions

Abstract

The eponym is a part of the nomenclature of medicine. In 1848, R. Virchow described the enlarged left supraclavicular lymph node  (Virchow's  node),  which  he  uncovered  by  physical  examination.  He  believed  that  such  lymphadenopathy  occurs  in cases of stomach cancer (less often – with lung cancer), when the metastatic process spreads up the thoracic duct to the left supraclavicular fossa. He described the pathogenesis of this trait and proved its malignant nature. Russian authors, apparently,borrowed this eponym from German textbooks on medicine. In 1886, Troisier added to Virchow’s insights and presented a detailed substantiation for the increase in the size of the left supraclavicular lymph node. Troisier described its typical location above the middle third of the clavicle behind the clavicular portion of the sternocleidomastoid muscle. He considered this enlargement as a direct sign of the existence of a neoplasm in the abdominal cavity or in the pelvic cavity, breast cancer, tuberculosis, and syphilis.
n his opinion, identifying a diseased lymph node by physical examination does not indicate the exact location of the primary focus of the tumor, but will direct the diagnostic search in the right direction. Palpable lymph nodes in the supraclavicular fossa (Troisier-Virchow), as a rule, indicate a malignant nature. If the lymph node enlargement is due to tumor emboli in cases of stomach cancer, it should be referred to as Virchow’s metastasis. Troisier’s symptom can be detected due to the metastasizing of cancer of other abdominal organs and the small pelvis, lung, breast, esophagus and tuberculosis lesions.

Downloads

Download data is not yet available.

References

Loukas M., Bellary S.S., Kuklinski M., Ferrauiola J,

Yadav A, Shoja M.M, Shaffer K., Tubbs R.S. The

lymphatic system: a historical perspective // Clin. Anat.

; 24(7): 807– 816.

Weller C.V. Rudolf Virchow – Pathologist // The

Scientific Monthly.1921; 13 (1): 33–39.

Virchow R. Zur Diagnose der Krebse in Unterleibe //

Med. Reform. 1848; 45: 248.

Morgenstern L. The Virchow-Troisier Node: a Historical

Note // Am J Surg. 1979; 138(5): 703–705.

Onuigbo W.I.B. Metastatic cancer of the pancreas: Historical review// J Cancer Sci Clin Oncol. 2014; 1(1): 104.

Karamanou M., Laios K., Tsoucalas G., et al. CharlesEmile Troisier (1844 – 1919) and the clinical description of signal node history of oncology // J BUON.

; 19(4): 1133–1135.

Troisier C.E. L’adénopathie sus-claviculaire dans les

cancers de l’abdomen // Arch. Gen. Med. 1889; 1: 129–

, 297–309.

Ludwig J. Virchow-Troisier’s lymph node // J Clin Gastroenterol. 1991; 13(6): 720–721.

Troisier C.E. Titres et travaux scientifiques. Paris, Masson et Cie. 1901, p. 1–63.

Mizutani M., Nawata S., Hirai I., Murakami G., Kimura

W. Anatomy and histology of Virchow’s node // Anat

Sci In. 2005; 80(4): 193–198.

Negus D., Edwards J.M., Kinmonth J.B. Filling of cervical and mediastinal nodes from the thoracic duct and the

physiology of Vrchow’s node – studies by lymphography

// British Journal of Surgery. 1970; 57 (4): 267–271.

Kuiper D.H, Papp J.P. Supraclavicular adenopathy demonstrated by the Valsalva maneuver. 1969; 280: 1007–

Cervin J.R., Silverman J.F., Loggie B.W., Geisinger K.R.

Virchow’s node revisited. Analysis with clinicopathologic correlation of 152 fine-needle aspiration biopsies

of supraclavicular lymph nodes // Archives of Pathology

& Laboratory Medicine. 1995; 119 (8): 727–730

Downloads

Published

2018-02-28

Issue

Section

Articles

How to Cite

N. Krylov, N., V. Alekberzade, A., & A. Piatenko, E. (2018). Virchow’s node: historical and didactic features f the description of the eponym. History of Medicine, 5(1). https://historymedjournal.com/HOM/index.php/medicine/article/view/200