From the history of epidemiology of peptic ulcer disease in the 20th century: social factors and the prevalence

Authors

  • Nikolay N. Krylov FSAEI HE I.M. Sechenov First MSMU MOH Russia (Sechenov University) 8 Trubetskaya St., building 2, Moscow 119991, Russia Author

Keywords:

peptic ulcer, morbidity, social factors

Abstract

The dynamics of ulcer disease morbidity in Russia and the developed world from the end of the 19th to the beginning of the 21st century are analyzed. The recorded peaks of peptic ulcer disease morbidity in the 20th century coincide with World War I and World War II, as well as with the Great Depression. Materials from the seminal work Experience of Soviet medicine in the Great Patriotic War of 1941–1945” help to clarify the particular characteristics of peptic ulcer pathomorphism during global conflict. A sustained reduction of morbidity began to be recorded from the mid-1950s, while the frequency of complicated forms of the disease remained unchanged. Against this background, groups of patients exhibiting signs of social deprivation stand out. They are characterized by an increase in the incidence of peptic ulcer disease, complicated progressions and poor treatment  outcomes.  The  analysis  of  the  specifics  of  such  cases  of  peptic  ulcer  progression  can  be  most  justified  from  the standpoint of psychosomatic medicine, rather than the theory of infectious ulceration, as in this case the impact of persistent stress and/or depression in patients at risk is clearly demonstrated. The epidemiological aspects of peptic ulcer disease present an obvious model for the study of the relationship between the inherent psychosocial and behavioral characteristics of patients from the at-risk group, as well as external and socioeconomic factors in the occurrence of infectious disease. The dynamics of peptic ulcer disease from the 19th century to the 21st century show a distinct connection to global and local social conflicts, as well as an adherence to cyclic rhythms (circadian, annual, perennial) affecting biological systems. Violation of these circadian processes is reflected in both the development and pathomorphism of peptic ulcers. Thus, an analysis of the impact of global and local conflicts in peptic ulcer diseases from the perspective of the history of medicine is not just a look back at the past,”but also an attempt to rethink the etiopathogenesis of the disease.

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References

Jones F.A. Clinical and social problems of peptic ulcer. Br.

Med. J. 1957; 1: 719–723.

Sonnenberg A. Time trends of ulcer mortality in Europe.

Gastroenterology. 2007; 132: 2320–2327.

Moynihan B. Duodenal ulcer. Practitioner. 1907; 78: 747–

Opyt sovetskoy meditsiny v Velikoy Otechestvennoy voyne

–1945 gg. [Experience of Soviet medicine in the

Great Patriotic War of 1941‒1945]. Moscow: Medgiz.

Vols. 23–24. (in Russian)

Cruveilhier J. Maladies de l’estomac. In: de l’Anatomie

Pathologique du Corps Humain. Bailliere, Paris, 1835.

(in French)

Mayo W.J. Chronic duodenal ulcer. JAMA. 1915; 44:

–2040.

Graham D.Y. Changing patterns of peptic ulcer, gastrooesophageal reflux disease and Helicobacter pylori: a unifying

hypothesis. Eur J Gastroenterol Hepatol 2003; 15: 571.

Watkinson G. The incidence of chronic peptic ulcer found

at necropsy: a study of 20,000 examinations performed in

Leeds in 1930–49 and in England and Scotland in 1956.

Gut. 1960; 1: 14–30.

Ivy A.C. The problem of peptic ulcer. JAMA. 1946; 132:

–1059.

Morris J.N., Titmuss R.M. Epidemiology of peptic ulcer:

Vital statistics. Lancet. 1944; 2: 841–845.

Baron J.H., Sonnenberg A. Hospital admissions for peptic

ulcer and indigestion in London and New York in the 19th

and early 20th centuries. Gut. 2002; 50 (4): 568–570.

Bardhan K.D., Williamson M., Royston C., Lyon C.

Admission rates for peptic ulcer in the Trent Region,

UK, 1972–2000: Changing pattern, a changing disease?

Digestive and Liver Disease. 2004; 36: 577–588.

Bardhan K.D., Royston T.C. Change and peptic ulcer

disease in Rotherham. Digestive and Liver Disease.

; 40: 540–546.

McConnell D.B., Baba G.C., Deveney C.W. Changes in

surgical treatment of peptic ulcer disease within a Veterans

Hospital in the 1970s and the 1980s. Archives of Surgery.

; 124: 1164–1167.

Spicer C.C., Stewart D.N., Winser D.M.R. Perforated

peptic ulcer during the period of heavy air raids. Lancet.

; 1: 14.

Kornilova L.S., Zhuk E.G., Nikitin G.A. Processy

tsiklichnosti v techenie yazvennoy bolezni [Cyclic processes

in the progress of peptic ulcer disease]. Klinicheskaya

meditsina [Clinical medicine]. 2002; 10: 39–43.

(in Russian)

Zimmerman Ya.S., Belousov F.V., Tregubov L.Z.

Sostoyanie psikhicheskoy sfery bol’nykh yazvennoy

bolezn’yu [The mental state of patients with peptic ulcer].

Klinicheskaya meditsina [Clinical medicine]. 2004; 3:

–42. (in Russian)

Zimmerman Ya.S. Evolyutsiya strategii i taktiki lecheniya

Helicobacter pylori-zavisimykh zabolevaniy (po

materialam konsensusov Maastrikht-1–3; 1996–2005)

[The evolution of strategy and tactics for the treatment

of Helicobacter pylori-dependent diseases (based on

consensus reports of Maastrickht 1‒3; 1996‒2005)].

Klinicheskaya meditsina [Clinical meditsine]. 2007; 8:

–13. (in Russian)

Svanes C. Trends in perforated peptic ulcer: incidence,

etiology, treatment, and prognosis. World J Surg. 2000; 24

(3): 277–283.

Yermolov A.S., Smolar A.N., Shlyahovsky I.A.,

Khramenkov M.G. 20 let neotlozhnoy khirurgii organov bryushnoy polosti v Moskve [Twenty years of emergency

surgery of the abdominal cavity in Moscow]. Khirurgiya

[Surgery]. 2014, 5: 7–16. (in Russian)

Levenstein S., Kaplan G.A., Smith M. Sociodemographic

characteristics, life stressors, and peptic ulcer: a prospective

study. J. Clin. Gastroenterol. 1995; 21: 185–92.

Goulston K.J., Dent O.F., Chapuis P.H. Gastrointestinal

morbidity among World War II prisoners of war: 40 years

on. Med J Aust. 1995; 143: 6–10.

Gill G., Bell D. The health of former prisoners of war of the

Japanese. Practitioner. 1981; 225: 531–538.

Nice D.S., Garland C.F., Hilton S.M., Baggett J.C.,

Mitchell R.E. Longterm health outcomes and medical

effects of torture among US Navy prisoners of war in

Vietnam. JAMA. 1996; 276: 375–81.

Aoyama N., Kinoshita Y., Fujimoto S., Himeno S., Todo

A., Kasuga M., Chiba T. Peptic ulcers after the HanshinAwaji earthquake: increased incidence of bleeding gastric

ulcers. Am J Gastroenterol. 1998; 93: 311–316.

Pomakov P., Gueorgieva S., Stantcheva J., Tenev T.,

Rizov A. Ulcères gastro-duodenaux pendant la periode

d’une crise economique aigue [Gastroduodenal ulcers

during a period of acute economic crisis]. J. Radiol. 1993;

: 265–7. (in French)

Smith M.P. Decline in duodenal ulcer surgery. JAMA.

; 237: 987–988.

Pulvertaft C.N. Comments on the incidence and natural

history of gastric and duodenal ulcer. Postgraduate

Medical Journal. 1968; 44: 597–601.

Kawano S., Fu H.Y. Epidemiology of peptic ulcer disease in

the aged in Japan Nihon Rinsho. 2002; 60(8): 1490–1498.

Krylov N.N. Helicobacter pylori – prichina yazvennoy

bolezni? [Helicobacter pylori – the cause of peptic ulcer

disease?]. Vestnik khirurgicheskoy gastroenterologii

[Journal of Surgical Gastroenterology]. 2014; 1(2): 75–

(in Russian)

Vogt T.M., Johnson R.E. Recent changes in the incidence

of duodenal and gastric ulcer. Am J Epidemiol. 1980;

: 713–720.

el-Serag H.B., Sonnenberg A. Opposing time trends of

peptic ulcer and reflux disease. Gut. 1998; 43: 327–333.

Lewis J.D., Bilker W.B., Brensinger C., Farrar J.T.,

Strom B.L. Hospitalization and mortality rates from peptic

ulcer disease and GI bleeding in the 1990s: relationship

to sales of nonsteroidal anti-inflammatory drugs and

acid suppression medications. American Journal of

Gastroenterology. 2002; 97: 2540–2549.

Sung J.J., Kuipers E.J., El-Serag H.B. Systematic review:

the global incidence and prevalence of peptic ulcer disease.

Aliment. Pharmacol. Ther. 2009 ; 29(9): 938–46.

Wylie C.M. The complex wane of peptic ulcer: trends in

duodenal ulcer admission to 790 hospitals, 1974–1979.

J Clin Gastroenterol. 1981; 3: 333–339.

Primatesta P., Goldacre M.J., Seagroatt V. Changing

patterns in the epidemiology and hospital care of peptic

ulcer. Int. J. Epidemiol. 1994; 23: 1206–1217.

Spechler J.S. Peptic ulcer disease and its complications.

In Sleisenger and Fordtran’s Gastrointestinal and Liver

Disease. Ed. M. Feldman. 7th ed. Philadelphia, PA:

Elsevier, 2002. P. 747–781

Zaitsev O.V., Natalsky A.A. Sovremennye tendentsii

zabolevaemosti oslozhnennoy yazvennoy bolezn’yu [Modern

trends in the incidence of peptic ulcer complications].

Fundamental’nye issledovaniya [Fundamental research].

; 9(3): 400–403. (in Russian)

Denisova E.V., Nazarov V.E. Analiz mnogoletney dinamiki

zabolevaemosti yazvennoy bolezn’yu do i posle vvedeniya

v lechenie eradikatsionnoy terapii [Analysis of the longterm dynamics of the incidence of peptic ulcer disease

before and after treatment with eradication therapy].

Gastroenterologiya Sankt-Peterburga [Saint Petersburg

Gastroenterology]. 2011; 2(3): 8–10. (in Russian)

Lam S.K., Hui W.M., Shiu L.P., Ng M.M. Society stress

and peptic ulcer perforation. J Gastroenterol Hepatol.

; 10: 570–576.

Levenstein S., Prantera C., Scribano M.L., Varvo V.,

Berto E., Spinella S. Psychologic predictors of duodenal

ulcer healing. J Clin Gastroenterol. 1996; 22: 84–89.

Holtmann G., Armstrong D., Poppel E., Bauerfeind A.

et al. Influence of stress on the healing and relapse of

duodenal ulcers. Scand. J. Gastroenterol. 1992; 27:

–923

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Published

2017-02-28

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How to Cite

N. Krylov, N. (2017). From the history of epidemiology of peptic ulcer disease in the 20th century: social factors and the prevalence. History of Medicine, 4(1). https://historymedjournal.com/HOM/index.php/medicine/article/view/157