As of March 2022, more than 6 million people have died globally as a consequence of the extremely infectious viral disease produced by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), spread quickly around the world when the first instances of this mostly respiratory viral infection were initially recorded in Wuhan, Hubei Province, China, in late December 2019. As a result, the World Health Organization (WHO) was forced to declare it a worldwide pandemic on March 11, 2020. One of the most serious complication is cytokine storm which is term describe several disorders of immune dysfunction characterized by constitutional symptoms, systemic inflammation, and multiorgan dysfunction that can lead to multiorgan failure if inadequately treated.