Background: Diabetes mellitus (DM) is like a cluster of metabolic disorders characterized by high blood sugar levels, disruptions in carbohydrate, protein, and fat metabolism, progressive damage, dysfunction, and failure of various critical organs including the kidneys, eyes, nerves, heart, and blood vessels. Diabetes is expected to impact approximately 537 million people worldwide by 2021, with a global incidence of 10.5%. Because type 2 diabetes (T2DM) progresses slowly, patients should be evaluated for diabetic nephropathy (DN) at the time of diagnosis and every year thereafter.