ISSN 2409-5834
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Comparison of Efficacies of Sofosbuvir/Daclatasvir with Sofosbuvir/Ribavirin for Hepatitis C Virus Genotype 3 Treatment in a Tertiary Care Center in Karachi
Volume -10 | Issue -2
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BIOCHEMICAL PROFILING AND MOLECULAR CHARACTERIZATION OF BETA GLOBIN GENE OF BETA THALASSEMIA MAJOR PATIENTS IN PUNJAB, PAKISTAN
Volume -10 | Issue -2
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Fear of Negative Evaluation and Procrastination: Exploring the Mediating Role of Self-Efficacy and Self-Esteem in University Students
Volume -10 | Issue -2
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BIOCHEMICAL PROFILING AND MOLECULAR CHARACTERIZATION OF BETA GLOBIN GENE OF BETA THALASSEMIA MAJOR PATIENTS IN PUNJAB, PAKISTAN
Volume -10 | Issue -2
-
Fear of Negative Evaluation and Procrastination: Exploring the Mediating Role of Self-Efficacy and Self-Esteem in University Students
Volume -10 | Issue -2
The effect of the Organic Cation Transporters1 (OCT1) gene polymorphism on the therapeutic efficacy of metformin in type 2 diabetic patients in Basrah/ Southern Iraq
Main Article Content
Abstract
Metformin does not undergo metabolism inside the body and is excreted in the urine unchanged. The organic cation transporter1 (OCT1) is one of the most numerous hepatic transporters and has an essential function in the hepatic transport of metformin. The study objectives are to research the prevalence of two (single nucleotide polymorphism) SNP [rs12208357] and [rs72552763] of (OCT1) of SLC22A1 gene in type 2 diabetes mellitus (T2DM) patients in (Basrah city)/South of Iraq and to investigate the association between these SNPs and metformin efficacy. I
