Based on the analysis of some contexts of ancient authors and epigraphic material we are talking about the place that takes the function of Apollo Ietroos in a complex set of Apollo`s functions. This function is recorded as a cult epithet, especially in Istria and Olbia on the Black Sea. And why his son, Asclepius, and his descendants (Hygieia, Panakeya, Machaon, Podalirius) become major deities associated with the functioning of medicine of the temple in ancient Greece.