ISSN 2409-5834
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Comparison of Efficacies of Sofosbuvir/Daclatasvir with Sofosbuvir/Ribavirin for Hepatitis C Virus Genotype 3 Treatment in a Tertiary Care Center in Karachi
Volume -10 | Issue -2
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BIOCHEMICAL PROFILING AND MOLECULAR CHARACTERIZATION OF BETA GLOBIN GENE OF BETA THALASSEMIA MAJOR PATIENTS IN PUNJAB, PAKISTAN
Volume -10 | Issue -2
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Fear of Negative Evaluation and Procrastination: Exploring the Mediating Role of Self-Efficacy and Self-Esteem in University Students
Volume -10 | Issue -2
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BIOCHEMICAL PROFILING AND MOLECULAR CHARACTERIZATION OF BETA GLOBIN GENE OF BETA THALASSEMIA MAJOR PATIENTS IN PUNJAB, PAKISTAN
Volume -10 | Issue -2
-
Fear of Negative Evaluation and Procrastination: Exploring the Mediating Role of Self-Efficacy and Self-Esteem in University Students
Volume -10 | Issue -2
Preparation and Evaluation of Felodipine Drug Nanoparticles
Main Article Content
Abstract
The aim of this study is to formulate and evaluate felodipine nanoparticles using solvent anti solvent technology. Felodipine is a calcium-channel blocker with low aqueous solubility and bioavailability. Felodipine prepared as nano particles in order to improve its solubility and dissolution rate. Twelve formulas were prepared and different stabilizing agents were used with different concentrations such as poly vinyl alcohol (PVA), poloxamer 407 and HPMC k15. The ratios of drug to stabilizers used to prepare the nanoparticles were 1: 1 and 1:2.
