Breast cancer (BC) is a more common cancer among women throughout the world. In Pakistan, women diagnosed with breast cancer move to advanced stages due to lack of awareness results in delayed presentation and diagnosis. This alarming situation demands for introducing awareness sessions to lessen the hazards of the disease. This study aimed to determine the effectiveness of planned teaching program on Breast Self-Examination (BSE) and BE for degree college female students. Quasi experimental design was performed. Simple random sampling technique was used to select a sample of 120 participants following pretest to assess the awareness level of the participants before educational intervention and to administered on the same day after educational intervention, to examine the effects of educational intervention and after 03 months to assess the retention of the given information on the topic. The data was analyzed by SPSS software version, IBM – 25. Repeated Measure ANOVA was used to compare results of the pre-test, post- test and post-test after 3 months. Pairwise comparison was performed by following Post-hoc Tukey test which was used with 0.05 level of significance. There was statistically significant difference in scores on the pre-test and post-test results, pre-test and post-test after 3 months, and post-test and post-test after 3 months. Frequency and percentages of qualitative variables were calculated and presented in graphical form. The results of this study demonstrated that there was statistically significant difference between pre- knowledge scores and post-knowledge score. The post knowledge score was higher indicating that educational intervention had an affirmative effect on knowledge about breast cancer