Orthodontic treatment is made more difficult by the resulting unbalanced occlusal relation. Class I features are present on one side and Class II on the other in patients with Class II subdivision malocclusions. In these situations, the extraction of four premolars is to create a bilateral Class I molar relation, which requires patient compliance with the usage of Class II elastics. One such Class II subdivision malocclusion case that was handled with asymmetric extractions is presented in the current case report. This method preserves one premolar without compromising dental occlusion or aesthetics and is not dependent on patient cooperation.