Prevalence of Pseudomonas aeruginosa associated chronic and acute respiratory infections and role of antibiotics as antibacterial agents against isolated pathogens
P. aeruginosa associated respiratory infections
DOI:
https://doi.org/10.48047/HM.10.2.2024.1128-1145Keywords:
Pseudomonas aeruginosa, , modern day superbug, quorum sensing, virulence factors, respiratory infections, , antibiotic resistance, sleep deprivation actorsAbstract
- aeruginosa is the commonest problematic pathogen for acute as well as chronic pulmonary infections in humans. Objectives: Screening of pathogenic P.aeruginosa from acute through Endotracheal tract secretions and Blood, chronic through Bronchoscopy samples. Identification of pathogenic strains by biochemical testing and virulence assays and Antibiotic resistance sensitivity test was done. Method: Blood, sputum and endotracheal samples were collected. Isolation of bacterial strains was done by cetrimide agar media and a number of morphological, biochemical and virulence tests were done for confirmation of the presence of P. aeruginosa. Antibiotic sensitivity was done to check the sensitivity of bacterial isolate against different antibiotics. Results: The recent study showed the percentile of Pseudomonas respiratory infections as, Type II Respiratory Failure 18%, Type I Respiratory Failure 9%, Pneumonia 22%, COPD 9%, Septicemia 15%, Pneumothorax & Emphysema and Co-pulmonale 4%, RDS 5%, Asthma 6%, Chest filial injury and pulmonary odema was 2%. Conclusion: Rate of pulmonary infections due to P. aeruginosa was high among patients and antibiotic sensitivity test resulted that P. aeruginosa was a multidrug resistant pathogen and only few percent of antibiotics were effective against this pathogenic bacteria.
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