Study the prevalence and Multidrug-resistant (MDR) of Salmonella enterica isolated from human and animals
DOI:
https://doi.org/10.17720/95zrys34Keywords:
MDR: Multidrug resistance.Abstract
Salmonella enterica isolates from humans and nonhumans have antibiotic resistance patterns that are associated to diarrhea. Salmonella enterica infections are considered as a significant threat to humans in developed countries, with food animals being the primary source of infection. Multidrug-resistant (MDR) Salmonella are becoming more prevalent as a result of widespread antibiotic use in livestock and poultry production for a variety of objectives, including treatment and growth promotion, which has resulted in the evolution of antibiotic-resistant Salmonella, making treatment of Salmonella infections increasingly difficult with each passing year.
Salmonella was isolated and identified using enrichment media, selective media, and biochemical assays. Thirty-three (10%) of the 350 samples tested positive for human and domestic animal isolates. The majority of isolates with antibiotic resistance patterns were using antibiotics. Among isolated salmonella, the drug resistance patterns were Ciprofloxacin (45.5%), chloramphenicol (57.57%), ampicillin (66.66%), amoxicillin (39.33%), and oxytetracycline (51.51%). Human and poultry isolates had higher resistance than other isolates due to higher antibiotic use than other animals.
According to the findings, the prevalence of resistance isolates to ampicillin, oxytetracycline and is chloramphenicol is high, and their usage should be limited. Resistance to other antibiotics, such as amoxicillin, and ciprofloxacin is also on the alarming level. This necessitates consideration in future infection control and antibiotic stewardship efforts.
This research is essential for one health since that reports potential public health pathogens connected with cattle and is important for studying antibiotic resistance patterns.
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