THE ROLE OF LIDOCAINE INFUSION IN REDUCING POSTOPERATIVE PAIN AFTER LAPAROSCOPIC COLORECTAL SURGERY: A RANDOMIZED TRIAL

Authors

  • Sara Sadaqat Consultant Anesthetist, Social Security Hospital Author
  • Tariq Iqbal Associate professor anaesthesia. Khawja Muhammad safdar medical college sialkot Author
  • Usman Zeeshan Assistant professor, Abu Umara Medical and Dental College Author
  • Maria Arshad Assistant Professor, Anesthesia Jinnah Burn Unit, AIMC Author
  • Zahid Mahmood Cheema Healthcare Administrator / Anesthetist, CMH Author
  • Hira Aslam Assistant Professor of General Surgery Rashid Lateef Medical College Author
  • Farah Naz Tahir Associate Professor, Biochemistry Department, Central Park Medical College, Lahore Author

DOI:

https://doi.org/10.48047/1a3kyy52

Keywords:

Intravenous lidocaine, postoperative pain, laparoscopic colorectal surgery

Abstract

Postoperative pain management remains a critical component in enhancing recovery after laparoscopic colorectal surgery. Intravenous lidocaine infusion has emerged as a potential adjunct for analgesia, yet its efficacy in this context requires further elucidation. This randomized, double-blind, placebo-controlled trial aimed to assess the impact of intraoperative intravenous lidocaine infusion on postoperative pain and opioid consumption in patients undergoing elective laparoscopic colorectal resections. Eighty patients were randomly assigned to receive either a bolus of lidocaine (1.5 mg/kg) followed by continuous infusion (2 mg/kg/h) during surgery or an equivalent volume of saline. Postoperative pain was evaluated using the Visual Analog Scale (VAS) at 2, 6, 12, and 24 hours post-surgery, and opioid consumption was recorded. The lidocaine group demonstrated significantly lower VAS scores at all time points (p < 0.05) and reduced total opioid consumption within the first 24 hours postoperatively (mean difference: 15 mg morphine equivalents; p = 0.01). No significant adverse effects were observed. These findings suggest that intraoperative intravenous lidocaine infusion effectively reduces postoperative pain and opioid requirements in laparoscopic colorectal surgery, offering a viable strategy for enhanced recovery protocols.

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Published

2022-12-31

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Section

RESEARCH ARTICLE

How to Cite

Sadaqat, S. ., Iqbal, T. ., Zeeshan, U. ., Arshad, M. ., Cheema, Z. M. ., Aslam, H. ., & Tahir, F. N. . (2022). THE ROLE OF LIDOCAINE INFUSION IN REDUCING POSTOPERATIVE PAIN AFTER LAPAROSCOPIC COLORECTAL SURGERY: A RANDOMIZED TRIAL. History of Medicine, 8(2), 819-825. https://doi.org/10.48047/1a3kyy52