RANDOMIZED STUDY OF TRANSCATHETER AORTIC VALVE REPLACEMENT VS. SURGICAL VALVE REPLACEMENT IN HIGH-RISK PATIENTS
DOI:
https://doi.org/10.48047/HM.V8.I2.2022.813-818Keywords:
Transcatheter aortic valve replacement, Surgical valve replacement, High-risk patients.Abstract
This randomized study aims to compare the outcomes of transcatheter aortic valve replacement (TAVR) and surgical valve replacement (SAVR) in high-risk patients with aortic stenosis, focusing on clinical outcomes, procedural safety, and long-term survival. The objective was to assess the safety and efficacy of TAVR compared to SAVR in patients deemed high risk for conventional surgery. The study included 400 participants, equally divided into two groups, with data analyzed based on 1-year follow-up. The results showed a statistically significant reduction in 30-day mortality and postoperative complications, such as stroke, in the TAVR group (p<0.05). Furthermore, TAVR demonstrated superior hemodynamic performance and faster recovery times compared to SAVR. However, there was no significant difference in long-term survival rates between the two groups (p=0.24). This study offers new insights into the comparative safety and efficacy of TAVR over traditional surgery, especially in high-risk populations. The findings suggest that TAVR should be considered a viable alternative to SAVR for patients with aortic stenosis who are at high surgical risk. The implications of these results extend to clinical practice, guiding treatment decisions for high-risk patients and contributing to the growing body of evidence favoring minimally invasive approaches in cardiovascular surgery.
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Copyright (c) 2022 Muhammad Saeed Afridi, Zohdum Malik, Najeeb Ullah, Anum Pari, Naresh Kumar khurana, Muhammad Zarrar Arif Butt, Farah Naz Tahir (Author)
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