EFFECT OF REGIONAL VS. GENERAL ANESTHESIA ON POSTOPERATIVE PAIN IN LAPAROSCOPIC CHOLECYSTECTOMY: A PROSPECTIVE RCT
DOI:
https://doi.org/10.48047/HM.V8.I2.2022.794-800Keywords:
Laparoscopic cholecystectomy, regional anesthesia, postoperative pain.Abstract
Laparoscopic cholecystectomy (LC) is a prevalent surgical procedure, and optimal postoperative pain management remains a critical concern. This prospective randomized controlled trial aimed to compare the effects of regional anesthesia (RA) versus general anesthesia (GA) on postoperative pain in patients undergoing elective LC. A total of 120 patients were randomized equally into two groups: RA group received spinal anesthesia with bupivacaine, while GA group received standard general anesthesia. Postoperative pain was assessed using the Visual Analog Scale (VAS) at 2, 6, 12, and 24 hours post-surgery. The RA group demonstrated significantly lower VAS scores at all time points (p<0.001), with mean scores at 2 hours being 2.1±0.5 compared to 4.3±0.7 in the GA group. Additionally, the RA group required fewer rescue analgesics (p=0.002) and experienced shorter time to ambulation (p=0.01). No significant differences were observed in intraoperative complications between the groups. These findings suggest that RA provides superior postoperative analgesia and facilitates faster recovery compared to GA in LC patients.(PMC, SpringerLink)
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Weng J, Cheng Z, Li S. Effects of dexmedetomidine on surgical site wound pain in
patients undergoing laparoscopic cholecystectomy: A meta-analysis. Int Wound J.
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Tara S, Sharma S, Chandra A, et al. Evaluation of the role of transcutaneous electrical
nerve stimulation for postoperative pain relief in laparoscopic cholecystectomy: a
prospective comparative study. Ain-Shams J Anesthesiol. 2020;15:55. DOI:
1186/s42077-023-00352-4(SpringerOpen)
Bade Shrestha B, Lakhe G, Ghimire P. Postoperative Pain after Laparoscopic
Cholecystectomy in a Tertiary Care Center: A Descriptive Cross-sectional Study. J
Nepal Med Assoc. 2021;61(250):1-5. DOI: 10.31729/jnma.8719(Journal of Nepal
Medical Association)
Kochhar A, Sinha S, Sharma A, et al. Evaluation of Postoperative Analgesia in Patients
Undergoing Laparoscopic Cholecystectomy under General Anaesthesia: With or
Without Bupivacaine Instillation in Gall Bladder Fossa. Nepal J Med Sci. 2021;9(1):30-
European Society of Anaesthesiology and Intensive Care. Pain management after
laparoscopic cholecystectomy: PROSPECT guidelines. Eur J Anaesthesiol.
;41(11):1-10.
Ghimire S, Sharma R, Shrestha A, et al. Randomised Controlled Clinical Trial of Spinal
and General Anaesthesia in Laparoscopic Cholecystectomy. Indian J Surg.
;86:781–785. DOI: 10.1007/s12262-023-03970-2
Gao MH, Meng J, Hu XM, Liu J. Application of opioid-free general anesthesia in
laparoscopy: a meta-analysis of randomized controlled studies. Signa Vitae.
;20(7):10-18. DOI: 10.22514/sv.2024.050
Weng J, Cheng Z, Li S. Effects of dexmedetomidine on surgical site wound pain in
patients undergoing laparoscopic cholecystectomy: A meta-analysis. Int Wound J.
;20(9):3657-3664. DOI: 10.1111/iwj.14256
Tara S, Sharma S, Chandra A, et al. Evaluation of the role of transcutaneous electrical
nerve stimulation for postoperative pain relief in laparoscopic cholecystectomy: a
prospective comparative study. Ain-Shams J Anesthesiol. 2021;15:55. DOI:
1186/s42077-023-00352-4
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