The potential role and biological assessment of Cu doped manganese oxide nanoparticles
DOI:
https://doi.org/10.48047/Keywords:
Nanoparticles, , Copper, Manganese oxide, Antibacterial, Antifungal, AntioxidantAbstract
Nanoparticles have significant attention for potential applications in diverse fields like materials chemistry, medicine, environmental studies, agriculture, catalysis, information technology, biomedical sciences, optics, electronics, energy, and sensors. Recently, an alternative technique for biological evaluation of copper doped manganese oxide (Mn0.88Cu0.16O2) nanoparticles has been developed using plants, bacteria, fungi, and algae. This study was aimed to assess the antibacterial, antifungal and antioxidant activity of Cu doped manganese oxide nanoparticles. The work was conducted in University of Okara laboratory. Disc diffusion and well diffusion methods were used to test the nanoparticles for antibacterial activity against Escherichia coli, Staphylococcus aureus, and Bacillus subtilis strains. The antifungal and antioxidant activity was also assessed. When combined with 0.1 mg/ml ciprofloxacin, Cu-doped manganese oxide nanoparticles exhibited typical inhibitory effects against E. coli and Bacillus subtilis, with zone of inhibition values of 0.05, 0.075, and 0.1 mg/ml. However, they showed no antibacterial activity against Staphylococcus aureus, unlike levofloxacin, which had varying inhibitory effects. The nanoparticles lack significant antibacterial properties. Antifungal testing revealed a slight inhibitory effect on Fusarium equesiti only for three days, with no impact on Rhizopus Stolonifer. Notably, the nanoparticles displayed superior antioxidant activity, achieving 99% at 0.08 µg/ml, surpassing ascorbic acid's 86%. Thus, nanoparticles may serve as potent antioxidants. To conclude, the synthesized Cu doped manganese oxide NPs can be used as a novel antibacterial, antifungal and antioxidant agent in agriculture.
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