ISSN 2409-5834

Significance of combined Use of Neutrophil Gelatinase-Associated Lipocalin and Natriuretic Peptides for Diagnosis and Follow up of Patients with Chronic Kidney Diseases

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Rzaq Shailan Kurshead ,Arif Sami ,Qasim S. Al-Mayah ,Ghassan A. Al-Shamma


Background Natriuretic peptides (NPs), are a structurally related group of hormones or paracrine factors sharing a common function of increasing renal sodium excretion and, consequently, reducing expanded extracellular volume. The principal NPs in clinical use are NT-pro BNP and NT-pro CNP. There is some evidence that using NPs tests in emergency departments could replace many expensive tests, and shorten the hospital stay and cost of treatment. Objectives: To identify the significance of using NPs and NGAL for the diagnosis and/or follow-up of subjects with chronic kidney diseases (CKD) in comparison with routinely used markers.

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