ISSN 2409-5834

Preparation and analysis of PVC-Membrane Potentiometric diazepam-Selective Sensor Based on Molecular Imprinted Polymer

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Maryam Emad ,Yehya Kamal Al-Bayati


A molecularly imprinted polymer was used to make two electrodes (MIP). MIP was manufactured using Diazepam (DZP) as the template, Allyl chloride as the monomer, and Ethylene glycol di methacrylate(EGDMA) as the cross-linker. Non-imprinting polymers (NIP) were created using the identical composition, minus the template (Diazepam). Tritolyl phosphate (TTP) and dibutyl sebacate (DBS) are examples of plasticizers utilized in the PVC matrix to produce films. DIA-MIP electrode slope, detection limit, durability, and linearity range are evaluated. The outcomes of the selectivity measurements on the interfering cations (Al3+, Ca 2+, and K+) indicate that they do not inhibit Diazepam. The produced electrode exhibited a favorable response, including to conduct research on pharmaceuticals.

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