ISSN 2409-5834

A study of the protective effect of 5 Thiocyanatouracil against paracetamol overdose in rats

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Ibtihal J. Naoor,Nadheerah F. Neamah,Jawad K. Hasan

Abstract

A new chemical called 5-Thiocyanauracil (TCU) has been created and is being studied for its potential hepatoprotective, anti-inflammatory, and antioxidant effects. Against paracetamol (PA) overdose oxidative stress in female rats. The study's goal was to investigate data that TCU's protective properties against liver and kidney impairment brought on by PA in rats. Fifty female-rats were employed, classify to five groups; 10 rats each: Control group (C) received 2 ml distal water (DW). Group (PA) take 500 mg/kg/day of PA, TCU group received 50 mg/kg/day, while PA & TCU group, administered TCU 50 mg/kg/day followed by 500 mg PA

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