Method Development and Validation of RP-HPLC for Simultaneous Estimation of Aztreonam and Avibactam in Injectable Formulation

Authors

  • Garikipati Durga Sai, Edward Raju Gope, Shaik Munnisha Begam, Shaik Ayesha, G. Manisha, Kavala Nageswara Rao, Raghava Doonaboyina , Nirmala Korukola Author

DOI:

https://doi.org/10.48047/

Keywords:

Aztreonam, Avibactam, RP-HPLC, Simultaneous Estimation, Method Validation

Abstract

A simple, accurate, precise, and stability-indicating reversed-phase high-performance liquid chromatography (RP-HPLC) method was developed and validated for the simultaneous  estimation of aztreonam and avibactam in injectable pharmaceutical formulation.

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References

Tan, X.; Kim, H.S.; Baugh, K.; Huang, Y.; Kadiyala, N.; Wences, M.; Singh, N.; Wenzler, E.; Bulman, Z.P. Therapeutic Options for Metallo-β-Lactamase-Producing Enterobacterales. Infect. Drug Resist. 2021, 14, 125–142.

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Published

2026-04-11

How to Cite

Garikipati Durga Sai, Edward Raju Gope, Shaik Munnisha Begam, Shaik Ayesha, G. Manisha, Kavala Nageswara Rao, Raghava Doonaboyina , Nirmala Korukola. (2026). Method Development and Validation of RP-HPLC for Simultaneous Estimation of Aztreonam and Avibactam in Injectable Formulation. History of Medicine, 12(1), 30-48. https://doi.org/10.48047/