Formulation and In-vitro Evaluation of Mucoadhesive Buccal Films of Metformin Hydrochloride for Controlled Release

Authors

  • Velugu Pavan Kumar, Praveen Gujjula, D Raghava, Kavala Nageswara Rao Author

DOI:

https://doi.org/10.48047/

Keywords:

Metformin Hydrochloride, Mucoadhesive Buccal Film, Controlled Release, Solvent Casting, In-vitro Evaluation, Bioavailability, Drug Release Kinetics

Abstract

Mucoadhesive buccal drug delivery systems offer a promising alternative for systemic delivery of drugs by avoiding first-pass metabolism and enhancing bioavailability. This project focuses  on the formulation and evaluation of mucoadhesive buccal films

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References

Bailey, C. J., & Turner, R. C. (1996). Metformin. New England Journal of Medicine, 334(9), 574–579. https://doi.org/10.1056/NEJM199602293340906

Chemate, S. Z., Garje, V. N., & Gayake, S. A. (2016). Formulation and evaluation of metformin hydrochloride buccal patch. PharmaTutor, 4(7), 52–58.

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Published

2025-10-07

Issue

Vol. 11 No. 2 (2025): 11 (2) 2025

Section

Articles

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How to Cite

Velugu Pavan Kumar, Praveen Gujjula, D Raghava, Kavala Nageswara Rao. (2025). Formulation and In-vitro Evaluation of Mucoadhesive Buccal Films of Metformin Hydrochloride for Controlled Release . History of Medicine, 11(2), 135-153. https://doi.org/10.48047/