Design, Formulation and In-Vitro Evaluation of Sustained Release Matrix Tablets of Sitagliptin Using Natural Polymers

Authors

  • Gudala Harichandana, Praveen Gujjula, Dr. D. Raghava, Dr. Kavala Nageswara Rao Author

DOI:

https://doi.org/10.48047/

Keywords:

Sitagliptin, Sustained release, Natural polymers, Xanthan gum, Drug release kinetics, Matrix tablets

Abstract

Sitagliptin, a DPP-4 inhibitor, is widely used in the treatment of type 2 diabetes mellitus. However, its short biological half-life necessitates frequent dosing, which may affect patient compliance. This study aims to develop a sustained release matrix tablet formulation of Sitagliptin using natural polymers such

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References

Agrawal, P., Bundela, R., Shukla, K., Jain, G., & Singh, J. (2025). Formulation and evaluation of sustained release tablets of Sitagliptin. International Journal of Research Publication and Reviews, 6(1), 4803–4808.

Alwan, W., & Nestle, F. O. (2023). Psoriasis and its impact on quality of life: A comprehensive review. Psoriasis: Targets and Therapy, 13, 1–12.

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Published

2025-10-07

How to Cite

Gudala Harichandana, Praveen Gujjula, Dr. D. Raghava, Dr. Kavala Nageswara Rao. (2025). Design, Formulation and In-Vitro Evaluation of Sustained Release Matrix Tablets of Sitagliptin Using Natural Polymers . History of Medicine, 11(2), 61-66. https://doi.org/10.48047/