Design and Comparative Evaluation of Effervescent Tablets of Ibuprofen for Enhanced Solubility and Patient Compliance

Authors

  • Panneeru Madhavi, Praveen Gujjula, Dr. D Raghava, Dr. Kavala Nageswara Rao Author

DOI:

https://doi.org/10.48047/

Keywords:

Ibuprofen, Effervescent Tablets, Solubility Enhancement, Patient Compliance, Dissolution Rate

Abstract

Ibuprofen, a widely used non-steroidal anti-inflammatory drug (NSAID), is poorly watersoluble, which limits its bioavailability and onset of action. To address this, the present study aims to formulate effervescent tablets of ibuprofen to improve its aqueous solubility, enhance patient compliance—especially

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References

Aulton, M. E., & Taylor, K. M. G. (2017). Aulton's Pharmaceutics: The Design and Manufacture of Medicines (5th ed.). Elsevier Health Sciences.

Brahmankar, D. M., & Jaiswal, S. B. (2015). Biopharmaceutics and Pharmacokinetics: A Treatise (2nd ed.). Vallabh Prakashan.

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Published

2025-10-07

How to Cite

Panneeru Madhavi, Praveen Gujjula, Dr. D Raghava, Dr. Kavala Nageswara Rao. (2025). Design and Comparative Evaluation of Effervescent Tablets of Ibuprofen for Enhanced Solubility and Patient Compliance. History of Medicine, 11(2), 55-60. https://doi.org/10.48047/