History of Medicine


An Open Access Journal

Myofacial Pain and TMJ Disorders Botox Treatment with Oldness Affection

Zina Ali Daily
B.D.S,M.Sc.(Periodontic) Assistant Lecturer, College of Dentistry, University of Al-Ameed, Iraq-Karbala.
Nawres Bahaa Mohammed
B.D.S,C.A.B.M.S(Oral and maxillofacial surgery) Assistant professor, College of dentistry, University of Al-Ameed, Iraq – Karbala.
Muntathar Muhsen Abusanna
B.D.S,C.A.B.M.S(Oral and maxillofacial surgery) Assistant professor, University of Al-Ameed, College of dentistry. University of Al-Ameed, Iraq – Karbala.
Ban zuhair Ahmed
Department of periodontogy, Al-ESRAA university college, Baghdad, Iraq.



TMJD is a disorder caused by masticatory myoarthropathy, which can be treated with botulinum toxin injections. This study aims to determine the effects of BTX-A injections on joint click, pain intensity, deviation on opening and maximum mouth opening.

Materials and Methods

Male and female patients between the ages of 16 and 42 were included in the human sample, all of whom were experiencing myofacial discomfort, trismus, and TMJ noises due to temporomandibular joint dysfunction. Individuals receiving 100 U of botulinum toxin type A (BTX-A) injected at 100 mL per temporalis, lateral pterygoid and masseter muscle were enrolled in the trial. Each individual was randomly allocated to one of four groups.: 7 individuals, both male and female, aged 16-22, made up Group I. Patients aged 23-29 made up Group II, which also included 7 men. 7 individuals between the ages of 30 and 36 made up Group III. Group IV had 7 patients (aged 37-43) of both sexes experiencing myofacial discomfort due to temporomandibular joint dysfunction.

The clinical evaluation

This study evaluated damage to the teeth and gums from clenching and grinding, also known as bruxism or parafunction. Four key TMD symptoms were reported both before and after a BTX-A injection: pain level, maximum mouth opening, deviation on opening and joint click. Clinical effectiveness and safety were assessed ten days, 30 days, and 3 months following injection. Results showed that older patients in Group IV (older age) reported the highest mean and SD values for pain intensity, maximum mouth opening, joint click, and deviation on opening. Group III finished in second place, followed by Groups II and I. (younger age). Maximal mouth opening, joint click, and opening deviation all showed improvement in HS between the first (pre-treatment visit) and subsequent visits following BTX-A injection.


Oldness-related changes in neuromuscular junction physiology lead to muscle mass and strength loss, and the older group required larger doses of BTX-A than the younger group for treatment of temporomandibular joint problems and pain reduction.

Keywords: Myofascial Discomfort, Arthritis, Oldness, Botulinum Toxin, TMJ Problems. ,


From 2021

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I.M. Sechenov

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