Synthesis and characterization of some new prodrug polymer based on poly vinyl alcohol and study some application: as a biological model
Wisam Abdul Jaleel Jawad
College of science/ Department of chemistry/ University of Babylon. Iraq
College of science/ Department of chemistry/ University of Babylon. Iraq
Faris H. Mohammed
College of science/ Department of chemistry/ University of Babylon. Iraq
College of science/ Department of chemistry/ University of Babylon. Iraq
Abstract
This study was suggested for synthesis a new polymers for polyvinyl alcohol reaction with aspirin and paracetamol as drugs, and these drugs carry carboxylic and amide groups after it's conversation into acid chloride, and all probable techniques were used for identification the product compounds by FT-IR and 1H-NMR spectrums, controlled drug release, swelling, viscosity of polymers and solubility were measured. Finally the thermal analysis and biological activity were studied too.
Keywords: synthesis, characterization, paracetamol, polyvinyl alcohol, prodrug polymers. ,
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