Evaluation of Interleukin 17A Serum Level in Patients with Polycystic Ovarian Syndrome
College of Medicine, University of Karbala, Karbala, Iraq
College of Medicine, University of Karbala, Karbala, Iraq
College of Medicine, University of Kufa, Najaf, Iraq
College of Medicine, University of Kufa, Najaf, Iraq, Al-sader Teaching Hospital, AL-Zahraa Teaching Hospital, Najaf, Iraq.
Abstract
Background: Polycystic ovarian syndrome (PCOS) is a complex, enigmatic, and common disease. It is the most common endocrinopathy faced by reproductive-aged women and affects up to 1 in 5 women. Methods: This study is a case-control study that included 50 women with PCOS. Their ages ranged between 13 to 48 years old. The control groups included 50 healthy women between the ages of 14 to 49. A sandwich ELISA test measured the serum level of interleukin-17A. Results: The mean IL-17A serum level in PCOS cases was (11.46) and in control was (9.53). The standard deviation in PCOS cases was (9.50) and in control was (18.99). However, the association was significant (P =0.005) between PCOS patients' serum IL-17A and control. Conclusion: According to the current study, the serum level of interleukin-17A (IL-17A) was a highly significant relationship with PCOS patients compared with control; therefore, interleukin-17A may be used as a predictive marker for diagnosing PCOS.
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