Immunological and Bacteriological Study of Autism Spectrum Disorder
Israa Zuhier Hamad
Department of Biology; College of Science; Mustansiriyah University, Baghdad, Iraq
Department of Biology; College of Science; Mustansiriyah University, Baghdad, Iraq
Fatima Rammadan Abdul
Department of Biology; College of Science; Mustansiriyah University, Baghdad, Iraq
Department of Biology; College of Science; Mustansiriyah University, Baghdad, Iraq
Hanan Tariq Subhi
Department of Biology, Faculty of science and health, Koya, University, Kurdistan Region, Iraq.
Department of Biology, Faculty of science and health, Koya, University, Kurdistan Region, Iraq.
Abstract
Autism spectrum disorder (ASD) is an intricate neurodevelopmental disorder generally demonstrated in the first few years of life and treatment to persist into adolescence and adulthood. In this study was (50) total number of ASD patients. While 30 as controls from Baghdad. All isolates were obtained from the stool of patients and number of isolates Escherichia coli was (n = 4, 25%). While the results showed serum levels of interlukin-1β and IL-17a in Autistic patients by using ELISA technique, the mean level of IL-1β and IL-17a were higher in patient group (2275.89 ± 77.38pg/ml) , (1457.72 ± 35.66pg//ml) , than control group (429.33 ± 35.84pg/ml) , (963.64 ± 8.91pg/ml) respectively, this variance was significant ((P <0.001)).
Keywords: Escherichia coli, Autistic, IL-1β, IL-17a. ,
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