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A Study on the Role of Hypokalemia in Infections with Covid-19 Virus in Babylon province

Anwar Abd-Al-Hameed Kamal
Department of Physiology, College of Medicine, University of Babylon, Iraq
Shrooq Majeed Mohameed Saeed
Department of Physiology, College of Medicine, University of Babylon, Iraq.

Abstract

Introduction: Droplets from a person who has COVID can spread to others mostly through their cough or sneeze. The management of the contagion and eventual control of it, therefore, appears to depend on its early and correct diagnosis. Additionally, the fact that COVID infections can manifest clinically in a variety of ways, from not appearing in any significant to severe states, emphasizes the need for quick, easy, accurate, and early detection techniques. This article discusses the effects of potassium ions on human organ function and potential contributions to the development of COVID-19 disease. The study included 50 samples, 30 people had Corona diseases with hypokalemia and 20 without hypokalemia persons, but didn't get any medical treatment. All of the cases were checked, and the results of the patients and the control group were statistically compared. All tests and samples were done at Marjan Teaching Hospital in Babil province from June 2021 to November 2021. People between the ages of 17 and 60 years took part in the study. Potassium estimation methods for all samples from blood Samples examine by using emission photometry (colorimetric) or by blood electrolytes (ST-200CC) blood analysis. Results: By June 15, 2021, 50 patients with COVID-19 (15 women and 35 men; age [17–60] years) were admitted to hospital in Marjan Teaching Hospital in Babil province from June 2021 to November 2021, consisting of 30 patients had severe hypokalemia with covid -19, 20 without hypokalemia-, the results were significantly associated with the severity of hypokalemia (P<0.001),60% of severe and critically ill patients had hypokalemia which was most common among patients covid -19. Hypokalemia was mostly caused by K+ loss. They responded well to K+ supplementation. Conclusion, Due to the inhibition of the ACE2 enzyme, which controls blood pressure by controlling potassium's activity in several metabolic processes, the coronavirus lowers potassium levels, which in turn impacts respiratory symptoms and pulmonary function. The majority of COVID-19 patients have hypokalemia. Due to ongoing renal K+ loss brought on by the breakdown of ACE2, treating hypokalemia is difficult. A favorable prognosis is indicated by the cessation of K+ loss, and it may be dependable., As a result, it is important to keep track of potassium levels when the body is infected with the virus, which is what the research's findings targeted.

Keywords: COVID-19, ACE2, rennin-angiotensin system (RAS), potassium, ICTV ,

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