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Effect of infection with the giant liver fluke (Fasciola gigantica) on the Superoxide dismutase (SOD) in liver tissue naturally infected with parasite.

Nisreen Ali Al-Tamimi
Department of Biology, College of Education for Pure Science, University of Diyala, Iraq
Nagham Y. Al-Bayati
Department of Biology, College of Education for Pure Science, University of Diyala, Iraq

Abstract

The current study was conducted with the aim of assessing the level of antioxidant (SOD) in the tissues of worms, and tissues of liver cows infected with Fasciola gigantica and uninfected livers in order to determine the effects of Fasciola gigantica infection. Through the current study, which extends from 12/12/2021 to 30/7/2022, 1422 cows and sheep livers were examined from butcher shop in Baquba city, Diyala province. One hundred and seventy four of livers for cows, and 1248 livers of sheep were collected with 14 non-infected liver in current study. In this study, 25 liver samples were infected with Fasciola gigantica belong to cows with absence of infection in sheep. Pieces of infected and non infected livers (14 non infect liver) samples were taken and homogenized. The activity of the enzyme Superoxide dismutase (SOD) was measured by ELISA. The results of the current study showed that there is a clear significant difference in the concentration of this enzyme for each of worms and infected liver (P<0.05). The results also showed that there is a significant difference between the infected group and the control group in all the studied areas (P <0.05).

Keywords: Superoxide dismutase, Fasciola gigantica ,

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