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Vitamin D and bone density in chronic hepatitis C patients

Rabab Murtadha Abed
Department of Medical Laboratory Technologies, Kufa Institute, Al-Furate Al-Awsat Technical University, Najaf, Iraq, 07715081762.
Eatemad Abd Ali Abedulrhman Al shawi
Department of Medical Laboratory Technologies, Kufa Institute, Al-Furate Al-Awsat Technical University, Najaf, Iraq, 07715081762.
Salam Abbas Oleiwi
Department of Medical Laboratory Technologies, Kufa Institute, Al-Furate Al-Awsat Technical University, Najaf, Iraq, 07715081762.
Douaa abdulalhussain kadhum
Department of Medical Laboratory Technologies, Kufa Institute, Al-Furate Al-Awsat Technical University, Najaf, Iraq, 07715081762.
Mona Adel Ismail
Department of Medical Laboratory Technologies, Kufa Institute, Al-Furate Al-Awsat Technical University, Najaf, Iraq, 07715081762.

Abstract

Objective, As bone fragility is common in chronic hepatitis c the study asses to determine the level of vitamin D and bone density and to demonstrate the consequence of vitamin d insufficiency in patient of long standing hepatitis C. Material and Method, 45 individuals were taken as samples, patients with chronic HCV. DEXA was suggested to patients as a follow-up for their condition. An experienced radiology technician has been used as DEXA to evaluate the bone mineral density BMD on the anteroposterior lumbar spine views, bone markers also were evaluated in patient group and control group. Results The study found there was no significant difference between femoral neck and the spine in BMD between HCV patient and control group. The Trochanter and total femur BMD values of HCV mean show significantly low in the experimental group compare to healthy group. Bone mass measurements, Trochanter value (p-value =0.004) and all biochemical parameter are not significantly differed for patients compared to control. Conclusion, The study found no significant difference between viral hepatitis patients and control healthy subjects. Additionally, there was no significant differences in biochemical bone markers for other group.

Keywords: Hepatitis, Alkaline phosphatase, BMD, Hepatitis C Virus, Chronic HCV, ,

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